Application deadline: 6 July 2012

The Faculty of Medicine at the Norwegian University of Science and Technology (NTNU) announces a vacancy for a permanent full-time position as Professor/Associate Professor in Medicine (Electron Microscopy/Histology).

Together with the other academic staff at the Department, the successful candidate will be responsible for research, developmental activities and supervision in the fields of electron microscopy related to biology, medicine, and diagnostics, and for teaching in histology.

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The position is available immediately; the start date is negotiable
Application deadline: 22 June 2012

The Sars International Centre for Marine Molecular Biology (Bergen, Norway) is now offering a two-year postdoc position in a research group working on cell type and organ system evolution in invertebrates. The announced position focuses on the application of correlative and 3D electron microscopic techniques for integration of light microscopic gene expression and ultrastructural datasets. The project forms an integral part of collaborative efforts to uncover neural circuitry of evolutionary conserved cell types in the central nervous system of the emerging invertebrate model organism Platynereisdumerilii for analysis of animal nervous system evolution.

Extensive resources for Platynereisdumerilii are now established by several labs (gene knock down, transgenesis, advanced imaging tools) and genome sequencing is in process making this protostome representative a valuable model for molecular and evolutionary research.

The position involves a broad spectrum of electron microscopic methods from automated TEM and SEM imaging of serial sections, 3D image processing, axon tracing, immunogold studies and new developments in correlative light and electron microscopy for studying gene expression on the cellular level. The successful applicant will have a solid background in electron microscopy and interest in function and evolution of invertebrate nervous systems. Prior experiences in advanced 3D image processing and molecular biological techniques are advantageous.

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Job description

Several positions are available for Ph.D. students and postdoctoral fellows at the Institute of Cellular Biology and Pathology (1st Faculty of Medicine, Charles University in Prague).

Our Institute has a long standing program of research in the cell nucleus, particularly using modern techniques in microscopy. We have a complete suite of light and electron microscopes, with new acquisitions and laboratory renovations underway.
We employ mammalian cell lines, as well as model organisms such as C. elegans and Drosophila, to explore structure-function relationships in the cell nucleus. Chromatin organization, integration of the processes of DNA replication, RNA synthesis and processing including gene silencing in the context of a functional nuclear architecture and the structure of the chromatin fiber are all topics under study using the latest methods in microscopy. Correlative light-electron microscopy, cryo-electron microscopy, electron tomography, live-cell imaging, state of the art molecular biology, and super-resolution optical microscopy are used together to elucidate mechanisms of gene regulation and other important events in the nucleus. We also focus on developing the methods themselves

Scientists joining our team will work with an interdisciplinary group of biophysicists, cell biologists, and mathematicians. Interested applicants must possess good communication skills and be highly motivated. To apply, please send a curriculum vitae, a letter of interest, and a summary of research experience to Professor Ivan Raška

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Position is immediately available

At the Technische Universität Darmstadt, Department of Material- and Geoscience a position in the field of Transmissions Electron Microscopy is immediately available and focuses on the scientific supervision of the TEM laboratory. Beside several conventional TEMs, the Institute of Material- and Geoscience is equipped with a Cs- Probe-corrected JEM ARM 200F, which will mainly be under the responsibility of the successful candidate. Due to a range of international research projects and three centres of excellence, the candidate will find a demanding but exciting scientific surrounding

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Closing date: 10 June 2012

EMBL is searching a Team Leader and Head of its electron microscopy core facility (EMCF). The team currently comprises a mixed service and research team (jointly affiliated with EMBLs Core Facilities & Services and Cell Biology and Biophysics units) with four members dedicated to service staff and four to research and development. It provides advanced electron microscopy, including electron tomography and correlative light and electron microscopy, services to EMBL and external users from EMBL’s member states. The facility furthermore regularly organizes international courses to train scientists in EM methods and actively collaborates with industrial partners to develop new applications of EM. In addition the facility collaborates closely with EMBL’s Advanced Light Microscopy Facility, EMBL’s mechanical and electronic workshops and in-house research groups for new EM technology development.

In addition to organizing and providing highest quality service in EM, it is therefore desirable that the future Team Leader also has an interest in EM methods development in order to maintain the technology at the cutting edge and extend the facility’s service portfolio to enable new biological applications. Such new methods could include, but are not limited to, new 3D EM methods (e.g. serial scanning methods), automation for high throughput EM, new correlative EM methods or new data analysis methods. Methods development could be driven by an independent interest in biological questions that can be addressed by EM or by a keen interest in scientific collaborations with biological research groups at EMBL. If appropriate, a joint appointment as a research Team Leader in one of EMBL’s biological research Units, as is currently the case with the Cell Biology and Biophysics Unit, is foreseen to strengthen and support these interactions.

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Position available until 2015 with possibility to extend

A postdoctoral position is available in the laboratory of Dr. Guy Hagen, at the Institute of Cellular Biology and Pathology (1st Faculty of Medicine, Charles University in Prague).

Our group works on developing one of the most exciting new methods in biology: superresolution microscopy. We are using multiple approaches including PALM/STORM imaging and structured illumination. We are actively engaged in developing these methods to push their performance in new directions. Our group is developing new instrumentation and new data analysis methods.

We are also using superresolution microscopy to study the functional organization of proteins in the plasma membrane, especially receptor tyrosine kinases which are potentially involved in cancer. We use state of the art equipment and techniques to investigate clustering of membrane proteins, and develop new methods in superresolution microscopy. Postdocs joining our team will work with an interdisciplinary group of biophysicists, cell biologists, and mathematicians.

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Closing date: 18 May 2012

The recent invention of the Helium Ion Microscope revolutionized imaging; moreover, it made nanofabrication with nanometer resolution possible.

The two PhD candidates will (further) develop and implement nanofabrication (lithography, direct write / milling, and ion beam induced processing) with this extreme beam.

Example research topics of the development are attainable resolution, pattern transfer and novel resists. For the implementation, actual nanodevices will be designed, fabricated and studied in collaboration with expert groups at the Kavli Institute of Nanoscience in Delft and at other universities and nano-tech companies. These devices include photonic crystals and plasmonic devices for sub-wavelength optics, templates for nano-imprint, and magnetic dots for high-density data storage.

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Closing date: 1 June 2012
Job Ref: R-579526/WWW

The Nano-investigation Centre at Liverpool (NiCaL) is established as a centralised facility that brings together analytical electron microscopy equipment and capabilities from around the University. We are looking to appoint 2 postdoctoral research associates as outreach officers, one with experience in SEM/FIB and the other with experience in TEM/STEM. You will have a PhD in Physics, Chemistry, Materials Science or a related subject and will be expected to provide support and analytical services for SME customers. This is a European Regional Development Fund supported project.

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Job description

This very hands-on position will give the qualified applicant many opportunities to pass on his or her experience gained through the use of analytical attachments for SEM and SEM/FIB microscopes. Key activities for this position will include teaching practical classes on the operation and application of analytical techniques associated with electron microscopes. This valuable Staff member will interact with Faculty and students as an in house consultant to facilitate research and help our customers obtain the best possible result from our lab. The Analytical Microscopy Instructor will be the primary contact for users of several advanced analytical tools such as WDS, EBSD, EDS, EBID and IBID, nano-manipulator/prober and ESEM. Our desire is to identify a Candidate who is seeking to be fully engaged with the teaching and practice of analytical microscopy.

The qualified applicant will posses wide ranging skills, while our research emphasis will favor those with hard materials experience the applicant will need to be familiar with hydrated, soft, and non-conductive sample techniques as well. The selection committee will give significant weight to hands-on experience the candidate has gained during his/her research or lab career. The ability to communicate and demonstrate understanding of the details of each technique will be most important for success in this position. A broad understanding of semiconductor fabrication techniques as well as experience working with semiconductor materials is desirable.

Primary Responsibilities:

1. Provide hands-on instruction on operation of WDS, EBSD, EDS, EBID and IBID, nano-manipulator/prober systems. Prepare materials and examples for training sessions, record and track training; arrange advanced training sessions from equipment suppliers.
2. Provide research support through consultation with users on equipment use, set-up and capabilities.
3. Maintain operational availability analytical equipment. Track and resolve system maintenance issues, communicate tool availability, anticipate requirements for spare parts, consumables, etc.
4. Advise and assist users with sample preparation and maintain SEM sample preparation area.
5. Provide operator support as an equipment expert for challenging samples and special projects.

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Post available until 30 June 2014, with the possibility of renewal until 30 June 2019

Applications are invited for a Research Associate or Research Assistant in Electron Microscopy, funded by the Wellcome Trust, to work with Professor Margaret Robinson’s group at the Cambridge Institute for Medical Research on coated vesicles and membrane traffic. The successful candidate will participate in projects ranging fromimmunogold localisation of novel proteins (discovered by the lab through proteomics, genomics, and bioinformatics), to determining the phenotype of acute depletion ("knocksideways") of coat proteins in different cells and tissues, to investigating how HIV Nef hijacks clathrin and associated proteins to down regulate cell surface receptors. Two microscopes will be available: a new FEI Tecnai G2 Spirit BioTWIN TEM and an older 100 kV Philips CM100 TEM. For further information, please visit the Robinson lab website (http://www.cimr.cam.ac.uk/investigators/robinson/index.html)

Although the post could potentially be held by either a postdoctoral research associate or a graduate research assistant, a strong background in cell biology is essential. We are particularly interested in individuals who would be able to start up new techniques in the lab, such as correlative light and electron microscopy.

The funding forthis post is available until 30 June 2014 in the first instance, with the possibility of renewal until 30 June 2019. For further information, please visit the Robinson lab website http://www.cimr.cam.ac.uk/investigators/robinson/index.html

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Closing date: 1 May 2012
Date of appointment: 1 September 2012

Job description

• Performing analyses / experiments with transmission electron microscopes (TEM) and associated attachments (EDX, EELS) of EMAT in service of the academic staff;
• First-aid maintenance of the transmission electron microscopes (TEM) and associated attachments (EDX, EELS). Contacts with the manufacturers;
• Developing, installing, implementing, operational maintenance and protection of these systems and infrastructure;
• Acquisition and management of the necessary materials for the use of these systems and their associated attachments;
• Preparation and presentation of technical notes;
• Technical and substantial support of students, PhD students, researchers and visitors in performing analyses/experiments (demonstrations, adjustments, alignments, first-aid, …);
• Technical supervision of technical staff.
  You take into account the imposed instructions and regulations, with a view to achieving the objectives.

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Summary:

We are looking for a PhD student to develop and apply Stimulated Emission Depletion (STED) super-resolution microscopy in combination with Förster Resonance Energy Transfer (FRET) for detecting molecular interactions. The project will be carried out in close collaboration with the cell biology group of the Science Faculty of Utrecht university. The candidate will be responsible for developing and optimizing the optical architecture of a STED microscope equipped with a novel, state-of-the-art, detection system capable of detecting FRET. The candidate will closely collaborate with a PhD student in biology to carry out super resolution experiments on (living) cells and analyze results.

We are looking for a talented and enthusiastic candidate with an MSc degree or PhD in (applied) physics or a related subject. He/she must have an excellent knowledge of written and spoken English and a top 20% ranking during his/her BSc and MSc. Experience in optical engineering and knowledge of the photophysics of fluorescence and FRET is helpful.

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Summary:

A 1-year postdoctoral position is available immediately at Ecole polytechnique (Palaiseau, France) to carry out characterization by transmission electron microscopy (TEM) of multiwall carbon nanotubes for field emission devices. The growth is performed by direct-current plasma-enhanced chemical vapour deposition (dc-PECVD). The goal is to increase the field emissivity of the nanotubes by tuning the growth parameters. As there is a direct link between the crystalline quality of the nanotubes and their electrical conductivity, TEM observation is a key step in the process of the improvement of the nanotubes' properties. The candidate will have a PhD, either in materials sciences or with a strong materials science content, for which he/she used TEM as a characterization tool, and an experience in thin-film / nano-objects growth.

More detail:
The work will take place at “Laboratoire de Physique des Interfaces et des Couches Minces” (LPICM, CNRS UMR7647, École polytechnique), in the “NanoMaDe” team (NanoMAterials & DEvices). LPICM which is composed of ~100 people from ~20 nations (33 have academic permanent positions). LPICM is well known world-wide for its expertise in thin film deposition by plasma-type CVD techniques as well as for its expertise in film characterisation by optical means (ellipsometry, scatterometry, Raman scattering…). Since its creation in 2003, the “NanoMaDe” team has studied carbon nanotube [1-5] as well as their collective organization [6], their characterization and their integration into electronic devices. École polytechnique is located in Palaiseau, a nice suburban city, part of the highly competitive “Physics Triangle” (Orsay, Palaiseau, Saclay), situated at 20 km to the south-west of Paris. The laboratory is equipped with state-of-the-art home-made dc-PECVD reactors and Raman micro- and nano- spectrometers TEM is performed with CIMEX, the École’s centre for electron microscopy, equipped with a FEI CM30 (300 keV) and Jeol 2010F (field emission gun, GIF).

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Closing date: 29 April 2012
Ref: 001765

A new research associate position is available for 1+2 years to work with Prof Klaas Wynne on an EPSRC-funded project to study the phenomenon of amorphous-to-amorphous liquid-liquid phase transitions. This will involve the use of a new (2012) confocal fluorescence microscope equipped with a thermal sample stage and fluorescence lifetime imaging (FLIM) to study molecular environments in phase-separating pure liquids. The experimental work may also involve Raman microscopy, dynamic/static light scattering, and femtosecond laser spectroscopy. You are expected to carry out microscopy experiments on a range of liquids and to develop basic software tools for the analysis of microscopy images. The ability to work in a multidisciplinary environment with collaborators is essential. The successful candidate will also be expected to contribute to the formulation and submission of research publications and research proposals as well as help manage and direct this complex and challenging project.

The work will be carried out under the guidance of Prof Klaas Wynne in the Ultrafast Chemical Physics group in the School of Chemistry at the University of Glasgow (see http://www.chem.gla.ac.uk/staff/wynne/ and http://www.ultrachemphys.org/). The group has recently (2011) moved into newly refurbished laboratory space where a group of PhD students and postdocs carry out research using state-of-the-art lasers, microscopes, and other equipment.

URL (search reference 001765)

Closing date: 4th May 2012
Job Reference: E&PS-00839

Applications are invited for a highly self-motivated Research Associate, to develop and apply advanced electron microscopy techniques, to a range of challenging problems, in support of the Light Alloys Towards Environmentally Sustainable Transport: 2nd Generation (LATEST2) Research Programme. This will involve both TEM and SEM based analysis and 3D image reconstruction, but will focus on developing the full analytical capabilities of a new instrument a Magellan™ XHR SEM, the highest resolution SEM in the UK, in collaboration with FEI and Oxford instruments.

The post is based in the School of Materials within the University of Manchester and is funded by the Engineering and Physical Sciences Research Council (EPSRC) LATEST2 Programme Grant for a fixed term, ending 09 July 2014. LATEST2 is a major collaborative research activity with funding of over £6.6mn, aimed at addressing the future scientific challenges associated with the exploitation of light metals in transport; concentrating on the areas of forming, joining and surface engineering, with a view to facilitating the introduction of high performance multi-material designs.

Applicants should have experience of the advanced electron microscopy and materials research applied to structural materials as well as a Ph.D. or equivalent in Materials Engineering, Physics, or a related subject, involving high level electron microscopy. The successful candidate will also be expected to be highly computer literate and have good communications skills. Knowledge of Al, Mg, Ti alloys used in transport applications would be an advantage.

URL (search reference E&PS-00839)

Ref number SU 619-0906-12
Deadline for applications: 2 May 2012

Subject area: Transmission electron microscopy study of novel materials

The Department of Materials and Environmental Chemistry, Stockholm University is one of the leading departments in inorganic materials chemistry and structural characterization (www.mmk.su.se). We seek a post-doctoral scientist to perform electron microscopic investigation of the structural heterogeneities of polycrystalline materials and to develop corresponding analytical methodologies. The recruited candidate will work in a research group having strong on-going research activities on developing materials with tailored chemical and structural heterogeneities. Two new sintering techniques, namely Spark Plasma Sintering and Laser Sintering, are applied in the group as routine prototype engineering tools for generating tailored microstructures demanded for fundamental studies of the correlation between materials microstructure and properties.

Eligibility
The applicant should have a PhD in Chemistry or Physics or Materials Science and Engineering with a strong focus on electron microscopes. Hands-on experience in scanning electron microscopes and transmission electron microscopes is an advantage. The applicant needs to have a PhD not older than 3 years.

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Starting in September-October 2012
Deadline for applications: 31st May 2012

The position is available in the area of theoretical and experimental transmission electron microscopy in the fields of electron holography and in-situ experiments. The position is available for one year and could be extended up to three years.

The experimental work will be carried out on the newly installed Hitachi HF3300 I2-TEM microscope dedicated to holography and in-situ microscopy. The I2-TEM is equipped with a C-FEG emitter, a double-stage capability for abberation-corrected Lorentz-mode imaging, a B-Corr (Aplanator from CEOS), a triple biprism set-up and a GIF Quantum and is operable between 60 kV and 300 kV. Dedicated magnetizing stages, nano-indentors and straining holders will be available for in-situ experiments. Electron holography developments concern magnetic and electrostatic field mapping as well as strain mapping through dark-field holography. A modern specimen preparation laboratory including a dual-beam Helios 600i is also available.

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Closing Date: 6th April 2012

A new opportunity exists for a motivated individual with extensive experience in cryo-Transmission Electron Microscopy (EM) and a predisposition to work in a collaborative environment.

Cancer Research UK’s London Research Institute (LRI) and the National Institute for Biological Standards and Control (NIBSC) are looking for a cryo Electron Microscopist to work on single-particle projects with multiple research groups. The main purpose of the role will be to contribute to biomolecular research on the maintenance of genome stability and establish the use of structural EM as a tool for assessing next generation biological medicines.

The LRI Clare Hall Laboratories and NIBSC are located on adjacent sites in South Mimms, near Potters Bar, Hertfordshire. The Senior Scientific Officer (SSO) will be employed by Cancer Research UK (CR-UK) and will be seconded to the NIBSC Electron Microscopy Facility, which houses a 200kV JEOL cryo transmission electron microscope equipped with the JADAS automated data acquisition system and a 4k GIF Quantum.

The SSO will provide an outstanding single particle cryo electron microscopy service for scientists at both the LRI and the NIBSC by producing high quality and timely results on individual projects, from initial consultation through to sample preparation, data collection, image analysis and result interpretation. The successful candidate will also be responsible for:

Training LRI and NIBSC scientists in cryo-EM grid preparation, data acquisition and single-particle image processing.

Assisting with general laboratory support including maintenance of microscopes, sample preparation equipment and rooms.

Continuing with professional development in the field of single-particle EM, by attending courses/workshops, presenting work at scientific meetings, keeping abreast of the relevant literature.

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Starting date: July 2012
Ref: SAM-090312-PLCPO

The successful candidate will have to:

Propose, setup and coordinate R&D projects related to the development of scientific instruments based on charged particle beams (ion sources and columns, electron sources and columns, mass spectrometers, detectors, …)

Actively participate in the execution of the R&D projects

Make contacts and interact with instrument manufacturers in view of initiating new collaborations, sustaining existing ones and valorising the developments performed within the research projects

Make contacts and interact with academic partners and research labs in view of initiating new collaborations and sustaining existing ones

Communicate on the generated scientific results (conference, scientific publications, symposium, …)

Propose and write patent applications

Write scientific and technical reports and documents

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Starting date: July 2012
Ref: SAM-090312-CHRECPBI

The successful candidate will have to:

Participate in R&D projects related to the development of scientific instruments based on charged particle beams (ion sources and columns, electron sources and columns, mass spectrometers, detectors,…)

Interact with instrument manufacturers in the framework of joint R&D projects and in view of valorising the developments performed within the research projects

Interact with academic partners in the framework of joint R&D projects

Communicate on the generated scientific results (conference, scientific publications, symposium, …)

Write scientific and technical reports and documents

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Starting date: July 2012
Ref: SAM-090312-CHRECPO

The successful candidate will have to:

Participate in R&D projects related to the development of scientific instruments based on charged particle beams (ion sources and columns, electron sources and columns, mass spectrometers, detectors,…)

Interact with instrument manufacturers in the framework of joint R&D projects and in view of valorising the developments performed within the research projects

Interact with academic partners in the framework of joint R&D projects

Communicate on the generated scientific results (conference, scientific publications, symposium, …)

Write scientific and technical reports and documents

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Application deadline: 10th April 2012.

Candidates should have an internationally outstanding record of research expertise in the field of experimental solid state physics / materials physics, and should be willing to strengthen the field of physical and spectroscopic characterization of micro- and nanostructured materials with a pioneering research programme. Of particular interests are solids whose functional properties are based on the combination of different materials systems and their interfaces.

The focus should be placed around spectroscopic techniques, e.g. in the area of modern electron and x-ray spectroscopy, also in combination with optical techniques and possibly including large-scale research facilities.

It is expected that the candidate institutes a significant connection to the research interests of the established working groups of the department of materials research and physics, i.e. regarding the production and the characterization of functional materials, physics and physical chemistry of condensed matter, environmental physics and biophysics. Likewise interest for research activities within the Faculty of Natural Sciences, among others life sciences and geological sciences, is expected.

The professor must substantially engage herself/himself in research-run teaching activities within the bachelor and master studies for students of engineering science, materials sciences, as well as for physics teacher training.

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Closing date: 2 April 2012.
Job reference: IRC46084

Take this opportunity and you will support all scientific groups within the Institute, particularly the livestock and viral diseases group. Organised and proactive, you will ensure the smooth running of the bioimaging lab while preparing samples and training new users on a wide range of technology, including laser micro dissection (LMD) and cryostat.
Keen to receive training in the ISO9001 quality standard, health and safety, and staff career development, you will have a BSc in biological sciences or similar together with knowledge of cell biology. Intermediate expertise in Microsoft Excel and PowerPoint will be essential. An understanding of confocal or immunofluorescence (IF) microscopy would be desirable.

The Institute for Animal Health (IAH) is an institute of the Biotechnology and Biological Sciences Research Council (BBSRC). We work to enhance the UK’s capability to contain, control, and eliminate viral diseases in animals through highly innovative fundamental and applied bioscience.

We are operating a 12-hour, seven day, Continental working rota attracting an annual extra duty allowance of up to £7k based on individual salary. Due to our work, you must not live on any premises where cattle, sheep, pigs, goats, or deer are kept.

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Application deadline: 30 March 2012

Forschungszentrum Jülich is seeking an internationally respected scientist in a joint procedure with Heinrich Heine University Düsseldorf for the position of

Director (W 3)

of Molecular Biophysics (ICS-5) at the Institute of Complex Systems

The Institute of Complex Systems works at the interface between biology, physics and chemistry and bridges the gaps between research into soft matter, structural biology and cell physics in the Helmholtz BioSoft programme.

The successful candidate will be an internationally respected scientist in the field of structural biology and conduct basic research in biology or biomedicine. The focus of his/her work will be on the application and development of modern cryo-electron microscopy (preferably structural analysis of individual particles, tomography, diffraction in two-dimensional protein lattices) and/or the application of coherent X-ray radiation (e.g. PETRA III and X-FELs in Hamburg). The future director will bring together the scientific areas of atomic-resolution structural biology and integrative cell biology in an attractive and future-oriented concept.

In accordance with the “Jülich Model”, the successful applicant will also be appointed professor (grade W3) in Physical Biology at the Faculty of Mathematics and Natural Sciences of Heinrich Heine University Düsseldorf. Active participation in existing and proposed research collaborations of the two institutions is expected, as well as a contribution (2 hours a week per semester) to the biology and biochemistry courses.

Prerequisites for the position are a university degree in science or medicine, a Habilitation or equivalent scientific achievements, experience in leading a scientific team, as well as in the acquisition of third-party funds and in teaching.

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Application deadline: 15 of March 2012

Key tasks and duties

• Develop and manage the implementation of the Bitplane EMEA Sales Strategy in line with Business plans.
• Line management of designated employees ensuring staff are fully briefed, trained and equipped to carry out their roles effectively.
• Develop & expand the reseller network to ensure annual sales targets are achieved.
• Provide high level market /competitive information contributing to the overall strategic direction of the Company
• Provide formal weekly & monthly reports on territories with accurate account of regional booking status and forecast.
• Liaise with broader sales management and product management teams to ensure efficiency of regional operations and coherence of global operations.
• Travel as required across territory to build key business partnerships.
• Any other duties as may be reasonably be required from time to time by your line manager.

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Application deadline: 13 March 2012

The Centre for Microscopy, Characterisation and Analysis (CMCA) at The University of Western Australia is seeking suitable applicants for the position of Technical Operations Manager. CMCA is a core facility with $60M of unique, high-end characterisation infrastructure and 30 staff who provide expertise to more than 450 science and engineering-based researchers annually as well as making major contributions to the University’s research training function.

An opportunity exists to take a lead role in managing the CMCA’s technical facilities and operations to a world-class standard. The successful applicant will oversee the location of new and existing instrument platforms and the provision of supporting infrastructure and technical support. Active participation in the Centre’s state-based and national networks is also required. The successful candidate will establish and maintain high technical standards to maximise the Centre’s ability to meet technical operations goals and objectives. This is a strategic position and we are seeking applicants with exceptional people and project management skills, as well as asset or technical facility management experience to work closely with the Director and CentreManager as part of the Leadership Team.

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Application Deadline - 09 March 2012 12:00

The Materials & Surface Science Institute (www.ul.ie/mssi), at the University of Limerick, provides a centre of excellence generating fundamental research on topics of industrial significance in the fields of materials and surface science. The Institute houses a multidisciplinary team of scientists and engineers, who undertake research focused on the design of materials for Health, Transport, Energy, ICT and Clean Technology. There are five instrument scientists based in MSSI who oversee the operation of the instruments, develop new techniques and collaborate with researchers in MSSI and in industry. The Institute requires an Electron Microscopist to support and develop the microscopy suite, which includes a JEOL JEM-2100F field emission TEM, with STEM attachment for bright field (BF) and dark field (HAADF) imaging, a JEOL JEM 2011 microscope, a Hitachi SU-70 high resolution SEM with EDS, WDS and EBSD capability and a Focused Ion Beam (FIB 200) with secondary ion mass spectrometry.

We are seeking an outstanding candidate who is self-motivated, creative and career-oriented to join our research team. The successful candidate will report to the Director of MSSI or the nominee of the Director and will support the research activities of the Institute. Applicants must have a PhD in materials science/electron microscopy/ chemistry/physics/engineering or a related discipline. The successful candidate must be able to work individually and as part of a team and will:

• Have demonstrable knowledge of crystallography and diffraction techniques and extensive experience of scanning and transmission electron microscopy (SEM and TEM) of a range of materials, including nanomaterials, as evidenced by publication in peer reviewed journals

URL (Job ID 007547)

Start: March 2012

To strengthen their position as leading provider of in situ instrumentation for Transmission Electron Microscopy, Nanofactory Instruments are looking for an Application Engineer, to be positioned in Gothenburg, Sweden.

As Application Engineer in EMEA, you will work in tight collaboration with their Area Sales Director in EMEA, to drive sales and customer support. You will be in direct contact with electron microscopy laboratories at universities and companies in all countries in Europe. You will probably also make occasional travels to USA and Asia. The head office of Nanofactory Instruments is located in Gothenburg, Sweden, and you will establish a strong relationship with their R&D and marketing functions there. The position requires that you are able to work independently, but still as an integral part of their global team. They put very strong emphasis on your personal values and attitudes.

Tasks

• Customer demonstrations
• System installations at customer sites
• Technical and application sales support
• Technical and application customer support
• Application development

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Application deadline: before March 15th

NeCEN is the national centre for biological transmission electron microscopy (TEM) of the Netherlands. It has 11 partners: Leiden University, LUMC, TU Delft, Erasmus MC (together these partners form Medical Delta), Utrecht University, Groningen University, TU Eindhoven, Netherlands Cancer Institute, AMOLF, UMC St. Radboud and FEI Company.

NeCEN is currently looking for:

2 a 3 full time TEM Scientific Operators.

The TEM Scientific Operators are responsible for maintaining and operating the microscopes, and assisting and advising users in sample preparation and data analysis. They may be involved as well in developing or optimizing novel applications in biological TEM. We are looking for electron microscopists with extensive experience (3 to 5 years) in high resolution cryo-transmission electron microscopy of biological samples using either single particle analysis or electron tomography applications. A demonstrated track record (publications, references) and special expertise in sample preparation, data collection and/or image processing are required.

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Application deadline: 29th February 2012
Starting date: as early as possible

The division performs front line research in the fields of synthesis of thin films and nanoparticles, with emphasis on the development of novel plasma-based processes and functional materials. We seek a person to join the division and work as a specialist in electron microscopy, with focus on transmission electron microscopy (TEM). The position entails advanced sample preparation, determination of the atomic order on a sub-nanometer level using atomic-resolution microscopy and image simulations. Other types of microscopy (SEM, AFM, STM) may also be a part of the position’s responsibilities.

Linköping University provides access to the Europe’s most advanced electron microscope (http://www.liu.se/forskning/forskningsnyheter/1.298749?l=en) as well as other state-of-the-art microscopy facilities.

In addition to the research activities, training of Ph.D. students within the Plasma and Coatings Physics division in the theory and methodology of microscopy techniques is expected.

The successful candidate will be employed as a senior research engineer, however a post-doctoral research position can be offered depending on the qualifications. The position is limited to two (2) years, but under certain conditions it can be transformed into a permanent position.

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Closing date: 26 February 2012

Monash University, in Melbourne, is seeking to appoint an outstanding postdoctoral Research Fellow with expertise in the area of advanced transmission electron microscopy of nanoparticles. The Research Fellow will conduct high-level research in the development and application of methods to characterise nanoparticles using aberration-corrected S/TEM and associated techniques as part of the research project "Understanding the interaction of light with matter at the atomic scale"

The Fellow will work closely with Professor Joanne Etheridge and the research team and instruments at the Monash Centre for Electron Microscopy and with Dr Alison Funston and her research team in nanophotonics. The Monash Centre for Electron Microscopy has a world-class suite of instrumentation, including a double-aberration corrected Titan3 80-300kV FEG-TEM.

The successful applicant will have advanced understanding and skills in the theory and application of TEM and a PhD or equivalent qualification and will possess sound interpersonal skills, along with excellent written and oral communication skills.

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Closing date: 24 February 2012
Vacancy ID: 101946

The Department of Materials seeks a specialist facility technical manager of the highest calibre with the ability to provide strategic leadership for a large, world-class electron microscope facility.

The post holder will provide leadership for the technical support of the suite of electron microscopes as well as co-ordinating the design and development of modifications to EM and ancillary equipment to meet research aims within the department.

Candidates should have significant experience as a service or development engineer with electron microscopes or with other comparable sophisticated high-performance scientific instruments, and should demonstrate a high level of expertise and technical skill in supporting a similar facility elsewhere. Your application should, therefore, demonstrate your substantial expertise in related technical areas, which may be confirmed either by a degree or an equivalent high level technical qualification as well as high level management and leadership skills.

URL (search for vacancy ID: 101946)

Fixed Term Contract for 36 months

You will join the new and expanding microscopy group at Warwick. The project aims to solve some long-standing problems in electron diffraction by employing computer control of a transmission electron microscope and associated data collection systems. You will use your expertise in scientific programming to automatically determine symmetry and information in diffraction patterns. There will be an opportunity to tackle significant theoretical challenges working with Prof. Römer in the theory group, developing robust techniques using Bloch-wave and multi slice models of electron diffraction, and with Prof. Thomas in the ferroelectrics and crystallography group to produce rapid and automatic crystal structure solution and refinement.

The work will be performed in the new Warwick centre for electron microscopy, using state of the art instrumentation including a double-corrected JEOL ARM200F and other transmission electron microscopes housed in the recently-completed Materials and Analytical Sciences building. The new technology you will participate in developing has direct applications in many areas, particularly multi-phase and multi-domain ferroelectrics, and there are opportunities for collaboration and interaction with several other research groups world-wide.

You should be about to attain, or possess, a PhD or equivalent in a relevant subject area (Physics, Mathematics, Computing, Engineering etc.) and are expected to have experience in scientific programming, preferably with some knowledge of the application of large-scale eigensystem solvers and multigrid methods for Schrödinger-type equations. Experience in image analysis and electron microscopy would be an advantage. You must be capable of working within a broader research team, demonstrate excellent written and verbal communication skills, and maintaining a current knowledge of the simulation literature. The ability to communicate research to an interdisciplinary audience will also be required.

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Closing date: 29th February 2012

A technician is required to contribute towards cell biology and imaging research in the Cell and Molecular Sciences group (based at the Dundee site). This post will provide support to members of the Cell Biology and Imaging Facility for sample preparation, routine screening, microscope care and maintenance, and support staff across JHI to provide routine imaging as appropriate.

The appointee should have experience of light microscopy and will learn to use and maintain light and confocal microscopes. Experimental techniques will range from plant infection and transient expression methods (e.g manual inoculation, agrobacterial infiltration, biolistic bombardment), through to specimen preparation techniques (e.g. fresh, frozen and fixed tissue, staining, antibody labeling, and in-situ hybridization). Demonstrated ability in sample preparation techniques (such as tissue dissection, fixation, sample embedding, and microtomy) would be an advantage but is not essential as full training will be provided. Some molecular biology skills (e.g. gel electrophoresis, restriction digestion, PCR, bacterial transformation and basic cloning) will be required in this post, as will some microbiological techniques, and previous experience would be beneficial.

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Closing date: 25 January 2012
Starting date: preferably 1 June 2012

DTU Energy Conversion and Storage is a new DTU institute holding world leading competences within the research and development of technologies for sustainable energy conversion and storage. Among these are fuel and electrolysis cells (for instance SOFC, SOEC, PEMs, solar cells and batteries. In addition we have world-class activities on a number of related topics exploiting functional ceramics: oxygen and hydrogen separation membranes, electrochemical flue gas purification and magnetic refrigeration. Key competencies include ceramic processing, solid state electrochemistry and advanced materials characterization.

To strengthen our activities in the Imaging and Structural Analysis Program we are seeking an outstanding Postdoc to initiate activities within in-situ transmission electron microscopy analysis of a variety of new energy materials. In combination with structural, crystallographic and electrochemical investigations, electron microscopy analysis is a crucial technique for understanding and modeling the behavior of new multiphase energy materials.

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Closing date: 14 February 2012 (11:30pm Sydney time) or until a successful individual has been identified
Reference No. 1995/1111

We currently seek a Postdoctoral Research Associate to work on an ARC funded project. This project aims to apply state-of-the-art in-situ deformation transmission electron microscopy techniques to reveal how crystalline defects in nanostructured metals and alloys interact with each other and to link directly the interactions with the mechanical behaviour of the materials. The results will enable structural design of advanced metallic materials with optimum mechanical properties.

This is an opportunity to work closely with Associate Professor Xiaozhou Liao and conduct research at the Centre for Advanced Materials Technology (CAMT) within the school. You will be part of a school which has a high international profile for its quality research over a wide field in materials characterisation and processing, nanotechnology, advanced manufacturing, solid mechanics and biotechnology.

Having completed a PhD in Material Science (or relevant area), you will have extensive experience in transmission electron microscopy (TEM) with a solid background and understanding in the structure and mechanical properties of materials.

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Job description

A two-year post-doctoral fellowship is available in the “Pixel” team of the Institutes for Structural Biology (IBS) and Technological Research for Life Sciences (iRTSV), Grenoble, France (http://www.ibs.fr/groups/dynamics-and-kinetics-of-molecular/pixel/?lang=fr). The project is financed by the French “Agence Nationale de la Recherche” (ANR).

GFP-like fluorescent proteins are markers of choice in fluorescence microscopy. In order to improve their performance, in particular for super-resolution (nanoscopy) applications, it is essential to understand their photophysical behaviour. We have acquired a state-of-the-art expertise in fluorescent protein’s photophysics (see refs) using structural biology approaches and we recently extended our expertise to super-resolution microscopy and single-molecule work. In this project, we will concentrate on photobleaching, in order to characterize the involved mechanisms, understand the role of environmental factors (redox potential, pH, oxygen), and design photoresistant candidates. We will use a vast panel of techniques, extending from single-crystal to single-molecule studies. The candidate will be responsible for the single-molecule part of the project.

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Closing date: 13 February 2012
Vacancy ID: 101820

This two-year postdoctoral research position, which is available from 1 April 2012, involves state-of-the-art in-situ electron microscopy characterisation of novel zero, one, and two dimensional nanomaterials, such as nanoparticles, nanotubes and graphene. The researcher will characterise in-house produced nanomaterials using state-of-the-art electron microscopy techniques including high-resolution transmission electron microscopy, analytical S/TEM, electron energy loss spectroscopy, X-ray energy dispersive spectroscopy, and high angle annular dark field imaging. The research group’s findings will contribute to the better understanding of the controlled manufacturing of nanomaterials with desired properties. This post, funded by the European Research Council (ERC), forms an important part of Professor Grobert’s ERC Starting Grant and may be extended up to a total of 3 years.

Applicants should have, by the start date, a doctorate in physics or materials science, preferably in the area of electron microscopy. You should have proven skills and previous experience in at least two, and preferably more, of the following: atomic-resolution electron microscopy, in-situ properties testing of nanomaterials in conjunction with analytical microscopy, electron energy loss spectroscopy, high-angle annular dark field imaging. Complementary techniques such as experience with in-situ STM-TEM, AFM/TEM, modelling etc. holders are desirable.

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Position available starting March 2012

A post-doctoral position is open at the Interdisciplinary Centre for Electron Microscopy (CIME), EPFL to conduct quantitative strain analysis in low power consumption integrated circuits using TEM. The project is in collaboration with an industrial partner, with the aim of solving problems of stress being created in Si transistors as device scales are reduced in their CMOS technology. A Ph.D. qualified applicant is required who has high competencies in TEM. Techniques expected to be applied in the project are convergent beam electron diffraction, nanobeam electron diffraction, and in-line dark-field holography for strain mapping. The successful applicant will join a dynamic team in a microscopy centre currently benefiting from an influx of new instrumentation. Because of the near start date of the project, applications will close soon.

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The position will be available starting 1st June, 2012

The Institute of Cellular Biology and Pathology (ICBP) of the 1st Faculty of Medicine, Charles University in Prague, is looking for a motivated young post-doc who acquired his PhD. degree in 2005 or later, with considerable experience in cryo-EM (single particle analysis, tomography) in structural biology. Candidates capable of leading an independent research project may be offered a group-leader position. We offer a competitive salary according to local standards in a well equipped laboratory for both fluorescence and transmission electron microscopy. The position will be available starting 1st June, 2012.

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Project

Nanostructures play key roles in a wide range of materials and devices because of their unique physical and chemical properties. These properties are controlled by the specific three-dimensional (3D) morphology and composition. Therefore, development of new techniques to determine the structure at atomic scale in three dimensions would allow the properties of the resulting materials to be fully understood and greatly enhanced, increasing the number of applications. Aberration-corrected (scanning) transmission electron microscopy ((S)TEM) is considered as one of the most promising techniques to achieve atomic resolution in three dimensions at a very local scale because of the strong interaction of electrons with small volumes of matter. However, the images provided by means of (S)TEM are two-dimensional projections of the object along the optical axis so that most information of the distribution of the object is lost in this third dimension. In order to reconstruct the 3D structure one has to resort to specialized 3D imaging techniques of which tomography is the most widespread. Tomography is the discipline of retrieving the 3D structure of an object from a series of two-dimensional projections which are obtained by rotating the sample about a rotation axis. The aim of this research project is to realize a breakthrough towards quantitative 3D reconstruction at atomic resolution using (S)TEM. The main focus in this project will be the theoretical investigation of different imaging modes and the development and implementation of new reconstruction schemes. The work performed within this project will take place at the University of Antwerp in collaboration with the Institute for Solid State Physics at Bremen University, and the Centrum Wiskunde & Informatica in Amsterdam.

The PhD candidate will be expected to:

• acquire knowledge in the field of electron microscopy (image formation and electron-object interaction), 3D reconstruction techniques, and statistical parameter estimation theory
• develop, implement, and apply (Matlab, C, or C++) new techniques to reconstruct unknown objects in three dimensions
• discuss the results in terms of the expected performance of the technique and fundamental physical limitations
• acquire knowledge in the field of electron microscopy (image formation and electron-object interaction), 3D reconstruction techniques, and statistical parameter estimation theory
• publish and present research results in the form of articles in international peer reviewed journals and papers at international conferences.

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Closing date: 15 February 2012

Recently, the group has purchased three in-situ TEM holders (STM-TEM and TEM-AFM from Nanofactory Instruments AB, TEM-Picoindenter from Hysitron Inc.) for nanomechanical and -electrical testing of materials. The holders will be employed for various studies in the Cluster of Excellence EAM as well as in two newly established collaborative research centers on Synthetic carbon allotropes (SFB 953) and Single crystal superalloys (SFB-TR 103). A particular focus will be on the mechanical testing of individual nanostructures, like e.g. metallic nanowires or nanoparticles, for understanding the effect of geometric constraints and pre-existing defects on the elastic and plastic properties. Another focus will be on electrical testing and microscopic manipulation of graphene and other carbon allotropes.

We are seeking a TEM expert (PostDocs) with a strong background in both conventional and high-resolution TEM and expertise in the application of in-situ TEM techniques, with a preference on nanomechanical testing. The successful candidate is expected to bring enthusiasm and a high degree of motivation and initiative for application of innovative in-situ TEM techniques in collaborative research projects.

The PhD student will apply in-situ TEM techniques in either of the above mentioned collaborative research projects making use of the newly established cutting-edge equipment. The candidate should have a master in physics, materials science, chemistry, mineralogy or a related discipline and be already familiar with conventional TEM and electron diffraction of materials. Most importantly, the candidates should bring enthusiasm for studying structure-property relationships of materials at the microscopic level.

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Closing date: 15 February 2012

Aberration-corrected HRTEM and nanoanalytical STEM-EELS/EFTEM studies play a key role in various collaborations within the EAM as well as in two newly established collaborative research centers on Synthetic carbon allotropes (SFB 953) and Single crystal superalloys (SFB-TR 103). For instance, the atomic structure and composition of core-shell and anisotropic nanoparticles (EAM), nanostructured organic and hybrid devices containing graphene and other C-allotropes (SFB 953) and structural and chemical gradients across interfaces in Ni- and Co-base superalloys (SFB-TR 103) will be studied by combining aberration-corrected HRTEM, STEM and nanoanalytical techniques at appropriate acceleration voltages.

We are seeking a TEM expert (PostDoc) with a strong background in conventional and high-resolution TEM and expertise in nanoanalytical TEM techniques, in particular STEM-EELS and EFTEM. The successful candidate is expected to bring enthusiasm and a high degree of motivation and initiative for collaborative research on nanostructured and functional materials with cutting-edge high-resolution and analytical TEM techniques.

The PhD student will carry out his/her thesis in one of the above mentioned collaborative research projects making use of the advanced analytical and high-resolution TEM techniques available at our FEI Titan³ 80-300 microscope. The candidate should have a master in physics, materials science, chemistry, mineralogy or a related discipline and be already familiar with conventional TEM and electron diffraction of materials. Most importantly, the candidate should bring enthusiasm for studying materials and their properties on the atomic and nanometer scale

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Job description

The INM - Leibniz Institute for New Materials has an opening for a staff scientist with a Ph.D. in Physics, Physical Chemistry, or Materials Science, and several years of experience in transmission electron microscopy, preferentially involving in-situ characterization, and EELS or EDX. The scientist will work in the newly structured group Innovative Electron Microscopy, and grow a research program in the field of in-situ aberration corrected electron microscopy for the characterization of nanomaterials at the atomic scale.

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Closing date: 31st December
reference IRC37795

Description of Project

The primary aim of this post is to establish a programme of research into virus structure including both isolated virus particles and virus-infected cells. The main role of the post-holder will be structural-investigation of medically important viruses by electron cryo-microscopy including development and/or implementation of techniques for three-dimensional reconstruction of symmetrical and non-symmetrical features to maximise the yield of biologically relevant information. As well as pursuing their own projects, the post-holder will be expected to work closely with other scientists and students in the Rixon and Bhella laboratories to help them produce high quality data from the cryo-microscopic images being generated within the CVR.

URL (search reference IRC37795)

Job description

At the Technische Universität Darmstadt, Department for Material- and Geosciences two PhD positions and one senior scientist research position (Habilitation) are available at the earliest convenience.

Both PhD positions are embedded in 1) a cluster of excellence (LOEWE-AdRIA; Adaptronic) and 2) a centre of excellence (SFB595, Electric Fatigue in Functional Materials).

Both PhD positions deal with the characterisation of the micro/nanostructure of different ceramic materials by means of REM and TEM. The preferential intention is to develop a relation between structure and properties of these materials.

In addition, a senior scientist research position (Habilitation) is immediately available. For further information regarding this position, please see the attached pdf-file.

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Closing Date: 12 Noon 06 January 2012

Prof Valeria Nicolosi has been awarded a grant from the European Research Council to study the development of supercapacitors based on two-dimensional nanomaterials and is looking for a postdoctoral research assistant with significant practical experience in high-resolution electron microscopy and electron energy loss spectroscopy (EELS). The post is available from 1 February 2012 for up to 2 years.

The successful candidate will be responsible for the structural characterisation of liquid-phase exfoliated 2Dnano-sheets by HRTEM/STEM and the investigation of their electronic structure by EELS. Working with members of Prof Nicolosi’s group they will also be expected to liaise with collaborators at the SuperSTEM facility, and the University of Oxford.

Applicants should have a PhD (by the start date) in Physics, Chemistry, Materials Science or a related discipline and experience in HRTEM/STEM and EELS. They should be well organised and self-motivated with excellent oral and communication skills, plus a strong publication record in internationally peer-reviewed journals.

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Starting at the earliest possible date.
The PhD positions will be for 3 years and the PostDoc positions for initially 2 years.
Deadline for application is 22 December 2011

The positions are available in the area of theoretical and experimental transmission electron microscopy. Possible topics include: a) 3D Strain mapping in semiconductor devices with sub-nanometer spatial resolution, b) Quantitative inline holography, c) Quantitative 3D electron diffraction and crystallography, d) Development of numerical tools to solve the dynamic inversion problem in electron diffraction from LARBED data, and e) Development of new electron optical devices.

The experimental work will be carried out in a well-equipped TEM laboratory featuring, among others, a unique 200 kV Zeiss EM922 TEM featuring a high-transmissivity corrected Omega-type in-column filter, an imaging aberration-corrected FEI Titan 80-300, and, in the near future, the Cs-Cc-corrected Zeiss SALVE microscope optimized for atomic resolution at accelerating voltages between 20 and 80 kV. A modern specimen preparation lab including also a triple-beam FIB is available as well.

Applicants should have either a masters (for the PhD positions) or a doctorate (for the post-doc positions) degree in physics, mathematics or materials science and should be skilled in at least one computer programming language (preferably C/C++, Matlab, or Python). Knowledge of (electron) optics, diffraction, and (dynamical) electron scattering theory, as well as hands-on (experimental) TEM experience would be an advantage.

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The position is available starting january 2012

The Institut Charles Sadron (ICS) and the Institut de Physique et Chimie des Matériaux de Strasbourg (IPCMS) are looking for a postdoctoral fellow with expertise in structural characterization of organic thin films and/or inorganic metal nanoparticles. The successful candidate will work within the european project HYMEC on hybrid thin films used in plastic electronics and will be in charge of the structural characterization of the films using Transmission Electron Microscopy. The candidate should have a good experience in Transmission Electron Microscopy (electron diffraction, tomographic analysis, EELS, EFTEM). However, motivated candidates with a strong background in advanced structural characterization of organic thin films will also be considered. The position is available starting january 2012.

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Key Activities

• Requirements engineering of new software products by taking into account market demands and applying current applications knowledge
• Specify functional behaviour and map out GUI of software to be developed
• Develop test plans and conduct blackbox and integration tests
• Manage projects while ensuring full compliance with defined processes and guidelines for software development
• Perform continuous bug and change management
• Assist sales organisation (product information, presentations and training as well as 3rd Level Support for technical and applications-related issues)
• Monitor software development projects for products relating to electron microscopy in the market

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Vacancy number V37.1470

Project: The project aims at developing the next generation of electron tomography for carbon-based and/or micrometer thick samples. Based on scanning transmission electron microscopy (STEM) the nanoscale organizational features of polymer nanocomposites will be studied which includes (1) Improving the understanding of the relevant contrast mechanisms in carbon-carbon systems, (2) Analysis of interfaces between fillers such as carbon black, carbon nanotubes or grapheme and the polymer matrix, (3) Exploring the limits for volume analysis of micrometer thick samples and determining the practical resolution/thickness dependencies. (4) Utilizing STEM tomograms for quantification of nanoscale network morphologies by image analysis.

Requirements: We are looking for an enthusiastic academically qualified physical chemist or material scientist with a strong interest in 3D nanoscale characterization by electron microscopy. The candidate should have affinity to multi-disciplinary and multi-analytical problems. Existing experience in electron microscopy, electron tomography, image analysis and ultramicrotomy is welcome. Given the scope of the project and the need for a close collaboration with the other team members as well as with the industrial partner’s excellent communicative skills and the ability to work in a team with chemists and physicists are prerequisites.

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Position description:

The nanomaterials chemistry and safety laboratory has a fixed term or post doctoral position for a TEM expert. This work is involved in a new characterization platform dedicated to nanosafety. Your missions:

• Participate to the TEM facility management,
• Develop technical preparation of several samples (vitrification, high pressure freezer…),
• Run experiments and characterizations
• Training end users partners of the nanosafety platform
• Participate to dissemination, communication

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The position is available immediately; the start date is negotiable.
Application deadline is December 05, 2011

The Sars International Centre for Marine Molecular Biology is offering one postdoc position for two years in a research group working on cell type and organ system evolution in invertebrates headed by Harald Hausen. The announced position is focused on the application of correlative and 3D electron microscopic techniques for integration of light microscopic gene expression and ultrastructural datasets. The project forms an integral part of collaborative molecular and microscopic efforts to uncover neural circuitry of evolutionary conserved cell types in the central nervous system of the emerging invertebrate model organism Platynereis dumerilli for analysis of animal nervous system evolution.

Extensive resources for Platynereis dumerilli have been recently established by several labs (gene knock down, transgenesis, advanced imaging tools) and genome sequencing is in process making this protostome representative a valuable model for molecular and evolutionary research.

The position involves a broad spectrum of electron microscopic methods from automated high-throughput imaging to immunogold studies as well as 3D image processing for axon tracing and generation of large scale 3D tissue atlases and reconstructions. Correlative microscopic analysis includes immunohistochemical and gene expression studies.

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The VIB Center for Advanced Microscopy is a multi-functional facility for bioimaging in Ghent Belgium, headed by Dr. Chris Guérin, which supports advanced research in diverse areas of the life sciences. The ambition of this Microscopy Core Facility is to become a centre of reference for advanced light, and electron microscopy. The facility is recruiting candidates for two post-doctoral fellowships.

Post-doctoral position in correlative light and electron microscopy (CLEM)

A post-doctoral fellowship is available beginning Jan-Mar 2012 to work on the development of three dimensional correlative light and electron microscopy. The post will be in the new VIB Center for Advanced Microscopy in Ghent, Belgium. The post will involve the use of advanced light and electron microscopes and the development of techniques to produce high resolution image stacks which can be precisely correlated in 3D using software developed for this purpose.

Post-doctoral position as Outreach Coordinator for advanced microscopy

The purpose of this position is to inform scientists at all levels (PI, post-doc, PhD students) within VIB of the capabilities and uses of advanced microscopy in cell biological research. Therefore, both a solid technical basis on the various aspects of imaging is required as well as a strong background in cell biology. The employee will be responsible for organizing a program of outreach education and training that will be made available and appropriately tailored to each VIB department. The employee will be available to consult researchers as early as possible in the design of image based experiments and will pro-actively pursue opportunities to do so.

To be maximally effective the employee will be required to achieve an expert level in all standard microscopic techniques that are provided by the Center for Advanced Microscopy, including knowledge of sample preparation, microscope hardware and software, acquiring high quality images and appropriate techniques for post-acquisition image processing. It will also be an advantage to participate in developing novel microscopy applications within the core including laser microscopy-based technologies and CLEM. The position will require familiarity with the most current literature on new developments, continuing education as available and participation in conferences on microscopy. When appropriate, new developments within the field should be tested and applied within the working group.

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Location: Home/field based with regular office visits

Key responsibilities:

• Primary interface with prospective customers for all EM-related products.
• Constantly uncover and pursue new business opportunities.
• Respond to enquiries in a timely and comprehensive manner.
• Maintain accurate forecasting and market tracking documents.
• Accurate and thorough completion of quotations and tenders.
• Representation of Hitachi at conferences/exhibitions/workshops.
• Propose and implement market stimulation and business development activities.
• Liaison with colleagues across Europe and in Japan regarding technical and commercial issues.
• Demonstration and application work on certain equipment, including preparation of detailed reports.

Core competencies:

• First-class sales acumen with a proven record of generating business growth in a scientific instruments environment.
• Broad understanding of science and engineering, with ability to translate complex research needs into the delivery of a commercially viable solution, whilst facing commercial and technical competition.
• Strong and enthusiastic cross-cultural communication skills with diverse audiences from lab technician to director level.
• Strong presentation and demonstration skills, including creation of professional and clear materials
• Basic understanding of domestic and international commerce

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Last application date for the project is November 20, 2011

Project: The purpose of the project is to realize the concept of complete automated 3D diffraction data collection and data processing for determining all atomic positions of nanometer-sized crystals and particles with an accuracy of 0.01 Ångström. In this case the electron crystallography method will be as fast and accurate as X-ray crystallography, but with the additional capability to study crystals and particles millions times smaller than those required for X-ray crystallography. The successful candidate will take part in the development of instruments (both experimental and theoretical) for a fast and automated data collection method which will allow acquisition of complete 3D data coming from transmission electron microscopes. The candidate should have a strong communication skill and ability to conduct international collaborations, and be self-motivated. Good knowledge of computers and programming are desired. The candidate should have a Master degree in Physics, Chemistry or Materials Sciences.

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Job description

JEOL are a leading supplier of Scanning Electron Microscopes (SEMs), Transmission Electron Microscopes (TEMs), Scanning Probe Microscopes (SPMs), Mass Spectrometers, NMR spectrometers, and Semiconductor tools for scientific and industrial purposes. We provide applications-specific solutions that advance our customers' diverse objectives — from routine analysis of organic and inorganic specimens to breakthroughs in nanotechnological development.

We are looking to recruit an Applications Specialist for Electron Microscope and related instruments. The key responsibilities will be,

1. Demonstrating the instruments for sales promotion
2. The analysis of samples which are received for the purposes of instrument evaluation
3. Supporting workshop events, exhibitions and training courses

The ideal applicant will have previous experience of SEM and TEM in an academic or industrial setting (although complete training will be provided on all instrumentation). Good presentation skills and the ability to communicate to people with a wide range of technical abilities are essential. A bachelor’s degree in a scientific discipline is a minimum requirement.

This position is based at our demonstration facility in Welwyn Garden City in the UK, however regular travel within the UK and abroad will be required.

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Closing date: 4 December 2011
Salary: £ 27,428 to £ 35,788 pa

A Post-Doctoral Research Associate position is available immediately in the development and application of electron tomography to study the 3D structure and distribution of particles in novel polymeric composite materials. The aim of the project, funded by the Michelin tyre company, is to investigate novel elastomeric composites for next-generation tyre compounds and especially to correlate, using electron tomography, the 3D nano-structure to the mechanical properties of the tyre compound.

The successful applicant will join the Midgley electron tomography group in Cambridge and work in collaboration with the Michelin research centre, based at Clermont Ferrand, France. The project will involve experimental microscopy (mainly STEM electron tomography), image processing, reconstruction and volumetric analysis. Applicants should have good experience of scanning transmission electron microscopy, electron tomography and image processing. Knowledge of polymer sample preparation using FIB and ultramicrotomy would be an advantage.

The position is available immediately and for up to 2 years.

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Closing date: 25 November 2011
Vacancy ID: 101342

Applications are invited from postdoctoral research assistants with demonstrable experience as a user of (S)TEM (with a special interest in quantitative nanoanalysis) and/or the atom probe, (ideally both techniques), to undertake research in the area of quantitative nanoanalysis of oxidation. The post is available for up to two years' duration in the Materials Department of the University of Oxford, starting as soon as possible. The appointed researcher will collaborate closely with researchers from the Electric Power Research Institute (EPRI, USA) and Areva (France).

The main objective of this characterisation project is to understand better early oxidation in Ni-based alloys used in nuclear reactors and, in particular, to study surface and grain boundary oxidation. Samples will be supplied by EPRI and the effect of alloy composition (Alloy 600/690) and water chemistry will be analysed.

With responsibility for the experimental work of this project, you will study the microstructure and chemistry of various nickel alloys prepared and tested in autoclaves by the project partners. State-of-the-art (S)TEMs and atom probes will be used to obtain high-resolution data of the chemistry and structure of the oxides. Techniques and strategies will be further developed for an accurate quantification of the microstructural regions of interest.

Applicants must have a doctorate in materials science, physics or a related discipline. Experience in sample preparation (mechanical polishing and FIB) is also required. For further details of the full selection criteria, you should read the job description (see link below). The closing date for applications is 25 November 2011 with interviews currently planned for the week of 12 December 2011.

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Closing date: 28th October 2011

As a Senior Scientific Officer in the Electron Microscopy Unit you will take on a range of projects using both transmission and scanning electron microscopy in collaboration with multiple research groups within the institute. Under the guidance of the core facility head you will also research and implement new imaging techniques and technologies. You will aid in day-to-day running of the unit including training scientists in electron microscopy, optimisation of protocols and maintenance of equipment.

The primary focus of the Electron Microscopy Unit is the provision of an outstanding electron microscopy service for scientists within the LRI, from initial consultation through to sample processing, electron microscopy, image analysis and data interpretation. We utilise a wide range of traditional and novel sample preparation techniques for transmission and scanning electron microscopy. We also develop new EM techniques and technologies in response to the samples and scientific questions received from the LRI research groups. In particular, we have pioneered the use of correlative light and volume electron microscopy in the biological sciences and developed novel techniques for X-ray imaging of soft tissues.

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Application deadline: November 10th 2011

We are looking for an individual to support services in transmission electron microscopy (TEM) for research projects. The activities include:

• Specimen preparation, imaging as well as analysis of results
• Train and advice users in electron microscopy and TEM sample preparation
• Assistance with day to day operations, including maintaining electron microscopes and ancillary equipment
• Contribute to the achievement of the annual quality objectives (ISO 9001:2008)

A background in high pressure freezing and in light microscopy will be an asset.

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Closing date: Monday 7 November 2011

In 2010, with the support of Seagate Technology, the Centre for Nanostructured Media established ANSIN - a new hub for collaborative research in advanced materials. In development of ANSIN we wish to appoint a new permanent position.

Lecturer in Advanced Materials Physics

The person will contribute to our objective of enhancing our existing programs of research in advanced materials and in particular those associated with data storage technologies.
Commencing 1 January 2012, or soon thereafter, the successful applicant will be appointed to enhance the research of the Centre for Nanostructured Media and will be expected to contribute to teaching on Physics pathways at undergraduate and postgraduate level

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Closing date: Monday 7 November 2011

In 2010, with the support of Seagate Technology, the Centre for Nanostructured Media established ANSIN - a new hub for collaborative research in advanced materials. In development of ANSIN we wish to appoint a new permanent position.

FEI Lecturer in Materials Microscopy

The person will contribute to our objective of enhancing our research programs and facilities for the microscopy of advanced materials.

Commencing 1 January 2012, or soon thereafter, the successful applicant will be appointed to enhance the research of the Centre for Nanostructured Media and will be expected to contribute to teaching on Physics pathways at undergraduate and postgraduate level.

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The duration of the post is 18 months in the first instance with start date of 1 March 2012

This Research Council funded post-doctoral research post involves electron microscopy of nanoparticle/cluster interactions with biological/environmental molecules, employing both cryo-TEM and aberration-corrected STEM techniques available in Birmingham.
The post is part of a major UK-US collaborative project (NanoBEE). The work will involve collaboration with Prof Jamie Lead in Environmental Research at Birmingham and US Universities including Rice.

A high level of scientific knowledge and experience in electron microscopy is required, including at least one of STEM and cryo-TEM and preferably also expertise in computer image processing/reconstruction.

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For fullest consideration apply by October 21, 2011

An Research Assistant Professor position is available in the Nanoscale Physics Group lead by Professor Robert F. Klie at the University of Illinois at Chicago to work on the application of atomic-resolution Z-contrast and annular bright-field imaging, as well as electron energy-loss spectroscopy (EELS) to functional nano-materials. The successful candidate will working with the group’s new aberration-corrected cold-field emission STEM (the JEOL ARM200-CF) with sub-Å and sub-eV resolution, equipped with several in-situ holders.

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The position:

Semiconducting nanowires have the potential to impact many technologies due to either their morphology or new materials properties. Moreover solar energy is one of the alternative solutions to reduce the used of fossil fuel. Crystalline Si is the main solution used for solar cell, and considerable efforts are dedicated to reduce cost. The purpose of this project is to optimize nano-heterojunctions geometries for photovoltaic (PV) application made from arrays of Si nanowires in order to propose reduced cost solution with optimum efficiencies.
Radial heterojunctions are elaborated and the structure and interfaces quality are key factors on the PV properties. The post doc will be involved in this large project and will concentrate his/her activity to use Transmission Electron Microscopy (TEM) to analyze these nanomaterials. The analysis on a nanometer scale and even more on atomic scale is a key point for understanding their PV properties. He/She will use state of the art equipments (probe and image cs-corrected FEI-Titan and FEI-Titan3), to perform high level microscopy: corrected high resolution Tem or STEM, analytical EELS and EFTEM to study interfaces in these heterojunctions. More over, holistic morphology will be study using 3D reconstruction either using electron tomography or Focused ion Beam.

The candidate will work within the electron microscopy laboratory of the Institute of Nanoscience and Cryogenic: www.inac.cea.fr/en/ based on the nanocharacterisation center on the Minatec campus (www.minatec.org/); He/She will also work in close association with the two labs developing the heterojunctions at the Institute Liten (www-liten.cea.fr/) and within another INAC lab.

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The position:

As Sales Account Manager you are responsible for managing sales/ account management activities for all assigned locations, defining and driving sales strategies, providing leadership to subordinates and ensuring the achievement of bookings, revenue and business goals.

Your primary responsibilities include the following:

• Own all sales/ account management responsibilities of specified FEI products to all sites including resolving any issues;
• Define, align and implement Account Strategy;
• Maintain accurate quarterly booking forecasts;
• Understand all budget issues at each customer and take strategic action;
• Confirm all system configurations, specifications and acceptance conditions are appropriate for closing orders;
• Manage all User Group activity by product as required;
• Manage system demonstrations by working closely with application engineers and product marketing managers;
• Manage the sales booking process;
• Manage product issues in the field by working closely with the Account service group and application engineers for solutions.

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Job Description:

In a group of engineers and physicists you will be responsible for performing the installation, the test and the factory alignment of advanced aberration correctors for transmission electron microscopes and similar instruments. In close cooperation with optics designers, electronics and mechanics engineers, and software developers you will evaluate and improve new instruments and techniques, update user documentation, and conduct training for field service and microscope users. You will take care of project schedules and production timing. If necessary you will help at the customer sites with installation, failure analysis and technical service.

This position requires a good technical and physical background, good communication skills and a responsible and organized way of work. A sound mathematical education is necessary. Some practical experience with a transmission electron microscope or other particle optics equipment would be a great advantage. A good command of the German and the English language is necessary.

We offer an attractive job in the stimulating scientific environment of modern particle optics instrumentation in a technology-driven company with friendly colleagues and good social and financial conditions.

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Job Description:

In a group of software developers and physicists you will be responsible for implementation and maintenance of our client/server based software and user interfaces for data acquisition, image analysis, and instrument control. Very good knowledge inC++ programming and scripting skills in Perl are necessary.
You should be used to cross-platform development in a mixed Linux and Windows environment. Some experience with the Qt widget set and the Debian installation and packaging system would be a great plus.
In close cooperation with physicists and engineers you will install and test the system software at our microscope prototypes and you will communicate with our customers about specifications and release cycles. A sound mathematical education, good technical background and a strong interest in science subjects is definitely necessary for this position. Some practical experience with the transmission electron microscope or other optics equipment would be a great advantage. Applications from scientists with a strong programming background are explicitly welcome. A good command of the German and the English language is necessary.

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Closing date: 21 September 2011
Job Ref: 5873

The School of Computing and Engineering is seeking to appoint a Research Fellow to collaborate with researchers at the University of Huddersfield in the use of electron microscopy to enhance a number of ongoing research projects in science and engineering.

You should be educated to PhD level in a science or engineering discipline, should have extensive experience of using either transmission electron microscopes or scanning electron microscopes and must be able to coordinate and organise multi-stranded research programmes. You must also have excellent oral and written communication skills and experience of using a focused ion beam system for specimen preparation would be an advantage. Candidates who have recently submitted a PhD thesis will be considered.

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Closing date: 01 October 2011

Project
Experimental models of CNS damage and repair are used to develop therapeutic interventions for the treatment of CNS conditions. Such interventions include cell transplants alone or in combination with different types of biocompatible biomaterials and nanoparticles for in vivo visualisation of cell grafts, tissue engineering and targeted delivery of genes, proteins and drugs. Ultrastructural analysis including electron microscopy will be used to elucidate cell-cell, cell-tissue, and materials-tissue interactions.

We are looking for
a talented, enthusiastic and creative scientist with a strong commitment to research. Excellent communication skills, both oral and written are important.

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Closing date: 30 September 2011

For its new electron microprobe and electron microscopy lab the Natural History Museum in Vienna is looking for a skilled operator/technician and lab manager. Experience with analytical electron microscopy and electron microprobe work is necessary, as is knowledge of computers and relevant programs. An excellent working knowledge of German and English is required.

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Closing date: 30 September 2011

The Centre for Microscopy, Characterisaton and Analysis (CMCA) at The University of Western Australia is seeking suitable applicants for a tenurable academic position (Assistant Prof/Associate Prof) to join the Centre's electron microscopy group, providing support to researchers broadly across the physical sciences/materials science and engineering disciplines (potentially in both SEM and TEM). A key role will be to provide renewed academic leadership in the field of scanning electron microscopy as a consequence of impending retirement.

The CMCA is a major central university facility that supports the research-intensive role of the university, forming a nexus for collaborative and interdisciplinary research linked to applications of our extensive microscopy and microanalysis capabilities, which include SEM, TEM, EPMA, ion probes, optical, confocal, flow cytometry, cell sorting, XRD, NMR and mass spec.

The successful candidate will have a background in the application of electron microscopy in the physical sciences. They will be expected to lead SEM-related activity in the Centre, including the provision of teaching/training, and driving future plans for SEM capabilities at the university. They will be encouraged to develop their own research programmes while also establishing collaborative and interdisciplinary research activities with local researchers.

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Closing date: 30 September 2011

The Lemke group at the EMBL studies interactions between intrinsically disordered proteins and structured proteins in vital processes, such as the nuclear transport machinery. Because such highly dynamic systems are inaccessible by most conventional approaches, the group applies a multidisciplinary approach combining single molecule and super resolution techniques with chemical biology tools. Recently the group developed a novel semi-genetic/synthetic strategy that substantially expands our ability to study protein machines both in the test tube and also in cells with extremely high spatial and temporal resolution.

We are now actively looking for a postdoctoral fellow with a strong interest in fluorescent techniques to push the temporal and spatial resolution limit of single molecule/super resolution techniques in biology. The goal is to combine biochemical single molecule FRET techniques with super resolution (such as PALM etc.) studies in cells to gain an unbiased view of the underlying protein plasticity.

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Closing date: 25 September 2011

The successful candidate will work in the Advanced Light Microscopy Facility at EMBL. (S)he will teach and support users in high content and high throughput microscopy technology. This includes all aspects of assay development with respect to automated high throughput image acquisition, image data analysis and large-scale data management. Post holder will also write custom software packages that allow users to conduct experiments at large scale automatically and if necessary develop custom hardware in collaboration with the EMBL workshops and industrial partners. (S)he will also develop custom software for image analysis of user data and will participate in the testing and establishing of cutting edge microscopy technology equipment in collaboration with the industrial partners of the facility. Post holder will participate in the organization and teaching of international courses on advanced and high throughput, high content microscopy techniques.

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Job description:

Nanoparticles are frequently used as additives in food and articles of daily use which necessitates studies of possible adverse effects on biological systems. In this context, the Laboratory for Electron Microscopy at Karlsruhe Institute of Technology (KIT) is recruiting a PhD student for an interdisciplinary project concerned with the detection of nanoparticles in cells. The PhD candidate with a Diplom/Master in physics is expected to use advanced electron microscopic techniques for nanoparticle detection in cells and image simulations to understand contrast formation. Further tasks involve the optimization of electron microscopic techniques and participation in cell culture experiments.

We offer a thorough electron microscopy education and top state-of-the-art equipment. The project will be carried out in close collaboration with biologists at the Institute of Toxicology and Genetics (KIT), who focus on toxicological aspects of nanoparticles uptake. Biological training will occur within the Biointerfaces International Graduate School at KIT.

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Job description:

The Agency for Science, Technology and Research (A-STAR) Singapore offers studentships (SINGA) for international students to undertake PhD degrees in Singapore: https://www.singa.a-star.edu.sg/

The Bob Robinson laboratory in the Institute of Molecular and Cell Biology (IMCB) uses structural biology techniques to study 1) how the power generated from actin filament polymerization is harnessed in different biological processes, 2) the breadth of structures and dynamics that are formed by diverse bacterial actin-like filament systems, and 3) how these structures may be interfered with in the search for novel antibiotics. The laboratory uses a variety of techniques, including: protein crystallography, electron microscopy, TIRF microscopy and SILAC mass spectrometry. The Robinson laboratory is looking for potential PhD students who would like to undertake a PhD in Singapore and are willing to apply for the SINGA scholarship in conjunction with the laboratory.

Details of the laboratory can be found at: http://www.imcb.a-star.edu.sg/php/robinson.php

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Applications: as soon as possible (preferentially until Aug 31, 2011)

We are looking for a highly motivated, team-oriented individual to work closely together with biologists on different types of microscopes (2photon-, fluorescence-, laser scanning-microscopes). Projects in the group include e.g. long-term intravital imaging experiments and characterisation of newly developed fluorophores.
Responsibilities of the position include the maintenance and continued development of our microscope setups as well as support in image analysis. The applicant is expected to have experience in techniques using light and fluorescent microscopy, image analysis and will need to have or develop an excellent understanding of 2-photon microscopy.

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Closing date: 1st October 2011

The hepatitis C virus (HCV) is a strict human pathogen, and hepatocytes are its main targets for productive infection. At the approach to the liver, HCV diffuses through the hepatic microenvironment (ME) where it comes in contact or interacts with several molecules of the extracellular matrix (ECM). The involvement in HCV entry of glycosaminoglycans and proteoglycans of the hepatic ME was suggested but remains unclear. Hepatocyte invasion involves a set of factors or receptors most likely acting in combination to accomplish virus cell entry. However these receptors are ubiquitously expressed at the surface of several cell types.

In this context, we aim at studying the role of components of the hepatic ME and ECM in the early steps of HCV entry into hepatocytes, in order to understand HCV hepatotropism.
The project is centered around two axes:

1. To follow the dynamics of HCV entry into primary human hepatocytes and hepatoma cells by fluorescence (time-lapse) confocal microscopy and by (cryo)-transmission electron microscopy (TEM);
2. To study the involvement of components of the hepatic ME and ECM in HCV entry, by combining cell biology and biochemical approaches, in collaboration with a group at the Ecole Normale Supérieure Lyon with a strong expertise in TEM and ECM biology (F. Ruggiero).

Our laboratory is part of the SFR Lyon Sud where all core facilities are available (http://www.ifr128.prd.fr and http://microscopies.univ-lyon1.fr), and is a core unit of the international pole of excellence and competitiveness in Infectiology “LyonBioPôle” (www.lyonbiopole.org).

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The position is available from October 2011 or soon after

Applications are invited for a postdoctoral position in scanning probe microscopy. The position is 1-3 years and is funded by the European Research Council (ERC) in a project headed by Associate Prof. Jeppe V. Lauritsen at the Interdisciplinary Nanoscience Center, Aarhus University, Denmark. The successful candidate will be joining a small team seeking to understand some of the cluster-support synergies and size-effects which have been revealed in catalytic systems, e.g. for transition metals on some metal oxides. A particular challenge and advance of the project is the application of non-contact Atomic Force Microscopy (nc-AFM) to atomically characterize relevant metal oxide surfaces and model catalysts based on real metal oxides or sulfides used in heterogeneous catalysis. In parallel, the project will be devoted to actual screening methods of the activity and selectivity of the well-characterized catalyst samples both under well-controlled vacuum condition and real high- pressure working conditions (high-pressure reaction cell). Collaboration with an industrial partner manufacturing catalysts is also part of the project.

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Closing date: 23 September 2011
Oxford Post Ref: 100697; Manchester Post Ref: EPS/12725

One, possibly two fixed-term Staff Scientists positions have been created to provide research leadership and user support at the SuperSTEM Laboratory, the EPSRC UK National Facility for Aberration-Corrected Scanning Transmission Electron Microscopy. Though based at the Daresbury Laboratory, one post will be associated with the Department of Materials at the University of Oxford, and the other with the Department of Materials, University of Manchester. The Universities of Oxford and Manchester, along with the Universities of Glasgow, Leeds and Liverpool, are the managing universities of SuperSTEM.

The Staff Scientist positions are created to undertake and lead aspects of research associated with aberration-corrected scanning transmission electron microscopy (STEM), to provide user support at a user facility, to contribute to the development of techniques, to contribute to gaining research funding, to be responsible for aspects equipment maintenance and development, and to undertake administration and other teaching as required. These posts are available immediately for a term of 12 months in the first instance. The SuperSTEM consortium is the successful bidder to operate the UK National Aberration-Corrected Scanning Transmission Electron Microscopy Research Facility, and on finalisation of the contracts these posts will be extended for at least a further 24 months.

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Job ID: 3080

FEI is a leading diversified scientific instruments company, featuring electron and ion-beam microscopes and other instruments for nanoscale applications across many industries: industrial and academic materials research, life sciences, semiconductors, data storage, natural resources and more. With a 60-year history of technological innovation and leadership, FEI has set the performance standard in transmission electron microscopes (TEM), scanning electron microscopes (SEM) and DualBeams(tm), which combine a SEM with a focused ion beam (FIB). FEI's imaging systems provide 3D characterization, analysis and modification/prototyping with resolutions down to the sub-Angstrom (one-tenth of a nanometer) level. FEI's NanoPorts in North America, Europe and Asia provide centers of technical excellence where its world-class community of customers and specialists collaborate. FEI has approximately 1800 employees and sales and service operations in more than 50 countries around the world.

The Applications Process Engineer is responsible for providing world-class applications process engineering to support customer sites worldwide. This position owns process development for customer's advanced technologies and other technical deliverables relating to advanced development and R&D efforts within FEI. The Process Development Engineer plans, manages and drives advanced development projects and investigates and defines new processing techniques.

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Closing date: 07 August 2011

This post is a Proposal for a post-doctoral project in High-resolution reconstruction of the Xenopus meiotic spindle in the Cell Biology and Biophysics Unit.

The post doc will work at generating tomograms from Xenopus spindles assembled in egg extracts. These tomograms will then be processed for image analysis by segmentation of sub-volumes in order to reconstruct the microtubules and their connections, in particular with the chromosomes and the spindle poles. Quantitative parameters will need to be extracted from the generated models so as to derive measurements of MT lengths, angles and respective distances in between them. From such numbers categories of MTs can be found out and various MT subpopulations defined, depending on their length, position and interaction with other MTs, chromosomes and spindle poles. This analytical part, which involves many aspects of computing, requires a well trained person able to handle computational analysis of the tomograms.

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Closing date: 07 August 2011

The Engineer will join the Electron Microscopy Core Facility, dedicated to cellular biology applications. The goal of the Core Facility is to provide high quality scientific services to the users.
The job responsibilities will include:

• Operating the microscopes to collect images and especially three-dimensional datasets for electron tomography for various projects
• Running computational data analysis packages including three-dimensional reconstruction of cell volumes and segmentation methods
• Training the new users and providing support for the existing ones in using TEMs and software packages
• Assist with keeping the microscopes maintained and in good working order
• Contribute to the upgrading of the facility's computer systems and software packages

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Closing date: 07 August 2011

The Senior Electron Microscope Engineer will administer the pool of eight transmission electron microscopes in EMBL's world class EM-facility. The microscopes cover a wide application range from low-end machines for specimen screening to high-end machines for high-resolution structural biology. The job responsibilities will include:

• Conducting introductions for new users to the microscopes, in particular those microscopes used for structural biology
• Providing assistance and trouble-shooting to microscope users
• Maintaining and servicing the microscope hardware and software at a basic level, as well as maintaining alignments of the electron microscopes
• Interacting with the microscope manufacturer and engineers to keep the microscopes maintained
• Sample preparation using different techniques in particular cryo methods
• Basic collection and evaluation of data for users and/or guests carrying out structural biology projects
• The post holder will also be able to pursue research interests which are related to the missions of the Unit EM groups

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Closing date: September 1, 2011

Project description: “Ultra-Sensitive Confocal Microscopy”
Confocal microscopy is a technology to make 3D images of fluorescently labeled biological objects. Since the first development of the confocal microscope in the early 80s the detection efficiency has been improved substantially by using more sensitive detectors, better optical design and improvements of the acquisition electronics. It is the aim of this project to further improve the sensitivity of the microscope. To do that we will exploit the novel technology, “Controlled Light Exposure Microscopy” (CLEM), invented and developed by prof. E. Manders and dr. R. Hoebe. CLEM has been designed for reduction of photodamage in fluorescence live-cell microscopy. In this project CLEM will be exploited to improve detection sensitivity. It is our aim to improve sensitivity by a factor of 50 to 100. In this STW-funded research project we have a post-doc positions available for a clever and enthusiastic scientist (physicist or optical engineer)Confocal microscopy is a technology to make 3D images of fluorescently labeled biological objects. Since the first development of the confocal microscope in the early 80s the detection efficiency has been improved substantially by using more sensitive detectors, better optical design and improvements of the acquisition electronics. It is the aim of this project to further improve the sensitivity of the microscope. To do that we will exploit the novel technology, “Controlled Light Exposure Microscopy” (CLEM), invented and developed by prof. E. Manders and dr. R. Hoebe. CLEM has been designed for reduction of photodamage in fluorescence live-cell microscopy. In this project CLEM will be exploited to improve detection sensitivity. It is our aim to improve sensitivity by a factor of 50 to 100. In this STW-funded research project we have a post-doc positions available for a clever and enthusiastic scientist (physicist or optical engineer).

The post-doc will concentrate on application of new light detectors in microscopy. He/she will extend a new microscope with dedicated detectors and the new electronics built by the PhD student. Apart from building a new microscope set-up, (s)he will also test the new set-up in biological experiments together with biologists. This project will be supervised by prof. Erik Manders (manders@uva.nl) at the FNWI-location of LCAM. In addition to a mail to PZ, please send a CC of your application to Manders.

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Job Type: Full time

The IMB Microscopy Unit (IMU) is a core technology platform of IMB whose mission is to provide optical imaging and image analysis tools with expertise to facilitate research in molecular, cell and developmental biology. The recent purchase of both a scanning electron microscope (SEM) and a transmission electron microscope (TEM) along with the associated sample preparation equipment will see the establishment of the Electron Microscopy Suite and will extend the techniques available in IMU to cover both optical and electron microscopy.

Duties and responsibilities:

• Carrying out sample preparation and electron microscopy for researchers
• Training, advising and supporting users in the application of electron microscopy techniques to biomedical research; from sample preparation, through image acquisition, to image processing and analysis
• Developing collaborative research projects with research staff
• Liaising with the manufacturers for repairs, upgrades and application support
• Organising international workshops, courses and conferences
• Trouble-shooting, providing basic maintenance and upkeep of microscope systems
• Performing other administrative duties

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